It makes complete sense of the prophecy given in the opening chapters of Genesis,
Genesis 3:15 15 And I will put enmity Between you and the woman, And between your seed and her seed; He shall bruise you on the head, And you shall bruise him on the heel." (emphasis mine)
There is a prophecy in Daniel of the last four world empires, and the final empire, an extension of what many believe is the Roman empire, but more are coming to believe is an extension of a Muslim empire; the scripture says:
Daniel 2:43 43 "And in that you saw the iron mixed with common clay, they will combine with one another in the seed of men; but they will not adhere to one another, even as iron does not combine with pottery.
And of the antichrist, in Revelation 13, it says,
Revelation 13:3 3 I saw one of his heads as if it had been slain, and his fatal wound was healed. And the whole earth was amazed and followed after the beast;
It seems that there is going to be a "seed" on earth that is not of God, but of the devil, the serpent of old, and according to Daniel, that there is a race that tries to mingle with the seed of men, but they will not adhere. Jesus told us that in the last days, it would be as the days of Noah (Mt. 24:37). In the days of Noah, the rebellious watcher angels had so corrupted the human race, that pure humans had almost disappeared.
This also makes sense with the scriptures that speak of the Antichrist receiving a fatal wound to the head, and being healed (Rev. 13:3). We all know of Wolvereine on X-Men, how he has a regenerative ability, and in one movie, takes a bullet to the head heals. That's a preview to how it will be when it happens to this one-world, new world order leader.
And this will be the mark of the beast. Not only will it allow for buying/selling, and retain all your medical history, tracking, etc, it will also repair your defective genes, thus protecting you from diseases and sicknesses that presently shorten our lives (Rev. 9:6). The people who take the mark of the beast will cease being a human, in the imagio dei, the image of God. They will be the "new humanity," made in the image of the Nephilim, in the name of preserving and improving the human race (through "evolution"). That is why no one who takes the mark of the mark of the beast will be able to be saved, they will have been made of the seed of Satan, and not the seed of man, for whom the Savior died (Jn. 3:16).